Boronic acid adducts of rhenium and radioactive isotopes of rhen

Organic compounds -- part of the class 532-570 series – Organic compounds – Radioactive metal containing

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424 11, 556 45, 556 37, C07F 1300, A61K 4300, A61K 4902

Patent

active

048718360

ABSTRACT:
Boronic acid adducts of radioactive isotopes of rhenium dioxime complexes are useful for labeling biologically active compounds as agents for radiotherapy. These boronic acid adducts of radioactive isotopes of rhenium dioxime complexes have the formula

REFERENCES:
patent: 4387087 (1983-06-01), Deutsch
patent: 4419339 (1983-12-01), Neirinckx
patent: 4434151 (1984-02-01), Byrne et al.
patent: 4615876 (1986-10-01), Troutner et al.
patent: 4647445 (1987-03-01), Lees
patent: 4652440 (1987-03-01), Paik et al.
patent: 4659839 (1987-04-01), Nicolotti et al.
patent: 4680338 (1987-07-01), Sandoro
patent: 4705849 (1987-11-01), Nunn et al.
patent: 4707544 (1987-11-01), Jones et al.
patent: 4714605 (1987-12-01), Feld et al.
Edward Deutsch et al., "The Chemistry of Rhenium and Technetium as Related to the Use of Isotopes of these Elements in Kerapeutic and Diagnostic Nuclear Medicine", Nucl. Med. Biol. vol. 13, No. 4, pp. 465-477, Int. J. Radiat. Appl. Instrum. Part B, 1986.
Eckelman, W. C. and Levenson, S. M., "Radiopharmaceuticals Labelled with Technetium", Int. Journal of Applied Radiation and Isotopes, 1977, vol. 28, pp. 67-82. Pergammon Press.
Jackels, et al., Simple Direct Syntheses of Iron Clathro-chelates Derived from Dimethylglyoxime and Boron Compounds, 1972, JCS Chem. Comm., pp. 1291-1292.
Jackels, et al., Synthesis and Characterization of Clathro Chelates Derived from Iron(II), Dimethylglyoxime, and Boron Compounds, 1973, Inorg. Chemistry, vol. 12, pp. 1232-1237.
Robbins, et al., Synthesis and Electrochemistry of Iron(II) Clathrochelates, 1985, Inorg. Chemistry, vol. 24, pp. 3381-3387.
Muller, et al., Synthesis and Characterization of a Ruthenium(II) 1986, Inorg. Chemistry, vol. 25, 2665.
Boston, et al., Synthesis and Study of Clathro Chelates Derived From Dimethylglyoxime, Cobalt and Lewis Acids, 1973, J. Amer. Chem. Soc., vol. 95, pp. 4163-4168.
Johnson, et al., {Tris[.mu.[(1,2-Cyclohexanedione Diozimato)-O O']Diphenyldiborato(2)-.multidot.-N,N',N",N'", N"",N'""}, 1983, Inorganic Synthesis, vol. 21, 112.
Jackels, et al., Iron(II) and Cobalt(III) Clathrochelates Derived From Dioximes, 1977, Inorg. Syntheses, vol. 17 pp. 139-147.
Deutsch, et al., Structural Characterization of a Bridged .sup.99 Tc-Sn-dimethylglyoxime complex; Implications for the chemistry of .sup.99 mTc-radiopharmaceuticals prepared by the Sn(II) reduction of pertechnetate, 1976, Proc. Nat'l Acad. Sci., pp. 4287-4289.
Brechbiel, et al., Synthesis of 1-(p-Isothiocyanatobenzyl) Derivatives and DTPA and EDTA. Antibody Labeling and Tumor-Imaging Studies. 1986, Inorg. Chemistry, pp. 2772-2781.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Boronic acid adducts of rhenium and radioactive isotopes of rhen does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Boronic acid adducts of rhenium and radioactive isotopes of rhen, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Boronic acid adducts of rhenium and radioactive isotopes of rhen will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-665245

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.