Bone substitute comprising fucans and methods of making and...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

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Details

C424S195170, C604S522000, C514S054000

Reexamination Certificate

active

07951391

ABSTRACT:
The present invention relates to the use of fucans with a weight-average molar mass of between 5000 and 100 000 g/mol, for the purposes of bone grafting, engineering and regeneration.

REFERENCES:
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Yutaka Kariya et al., “Isolation and partial characterization of fucan sulfates from the body wall of sea cucumberStichopus japonicusand their ability to inhibit osteoclastogenesis”, Carbohyd. Res., 339, 1139-1346, 2004.
Olivier Berteau, “Sulfated fucans, fresh perspectives: structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide”, Glycobiology, vol. 13, No. 6, 29R-40R, (2003).

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