Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1983-02-07
1985-01-15
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
548323, A61K 31415, C07D49504
Patent
active
044938411
ABSTRACT:
Imidazole derivatives of the formula ##STR1## wherein X is hydrogen or C.sub.1-4 -alkyl, Y is sulfur, sulfinyl or sulfonyl and Z is thienyl, optionally substituted by methyl or fluorine, or a group of the formula ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are hydrogen, methyl, fluorine, hydroxy, methoxy, methylthio or two of R.sup.1, R.sup.2 and R.sup.3 on adjacent carbon atoms taken together are methylenedioxy or ethylenedioxy or one of R.sup.1, R.sup.2 and R.sup.3 is mono- or di-(C.sub.1-4 -alkyl)-amino and the other two are hydrogen,
and physiologically or pharmaceutically compatible or acceptable acid addition salts thereof, are described. The compounds of formula I inhibit the aggregation of the blood platelets and have antihyperglycemic activity.
REFERENCES:
patent: 3185691 (1965-05-01), Pribyl et al.
patent: 3615607 (1967-03-01), Soma et al.
Wynberg et al., Chem. Abst., 63, 5630e (1965).
Boxer Matthew
Briscoe Kurt G.
Hoffmann-La Roche Inc.
Leon Bernard S.
Rotman Alan L.
LandOfFree
Blood-platelet aggregation inhibiting 4,5,7,8-tetrahydro-4,4,8,8 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Blood-platelet aggregation inhibiting 4,5,7,8-tetrahydro-4,4,8,8, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Blood-platelet aggregation inhibiting 4,5,7,8-tetrahydro-4,4,8,8 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1481078