Bis (biaryl) compounds as inhibitors of leukotriene biosynthesis

Details Bis (biaryl) compounds as inhibitors of leukotriene biosynthesis Bis (biaryl) compounds as inhibitors of leukotriene biosynthesis

1995-02-15

1996-11-19

Davis, Zinna Northington

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514365, 514374, 514422, 514444, 5462831, 548203, 548235, 548562, 549 60, 549283, A61K 3144, C07C31102, C07D40104

Patent

active

055763383

ABSTRACT:
Compounds having the Formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

REFERENCES:
patent: 5424320 (1995-06-01), Fortin et al.
J. Med. Chem., 35:2600-2609 (1992).

Affiliated with

Also associated with

Rating

Bis (biaryl) compounds as inhibitors of leukotriene biosynthesis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bis (biaryl) compounds as inhibitors of leukotriene biosynthesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bis (biaryl) compounds as inhibitors of leukotriene biosynthesis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-541336