Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.
Patent
1986-06-18
1990-11-13
Kight, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Scleroproteins, e.g., fibroin, elastin, silk, etc.
523105, 523111, 424485, 424 9564, 128DIG8, A23J 110, C08H 106
Patent
active
049702980
ABSTRACT:
This invention relates to a biodegradable collagen matrix having a pore size and morphology which enhances the healing of a wound. It further relates to a process for preparing the matrix. One embodiment of the invention comprises a biodegradable matrix which comprises collagen, hyaluronic acid and fibronectin. Other embodiments include a process which comprises freeze drying a dispersion containing collagen, crosslinking the collagen via two crosslinking steps and freeze drying the crosslinked matrix.
REFERENCES:
patent: 4193813 (1980-03-01), Chuapil
patent: 4440680 (1984-04-01), Cioca
patent: 4522753 (1985-06-01), Yannas et al.
Berg Richard A.
Doillon charles J.
Silver Frederick H.
Weadock Kevin
Whyne Conrad
Kight John
Nutter Nathan M.
University of Medicine and Dentistry of New Jersey
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