Biocompatible polymer blends and uses thereof

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

Reexamination Certificate

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Reexamination Certificate

active

10293974

ABSTRACT:
The present invention relates to a novel series of polymers which have been prepared by blending hydrophobic biocompatible, biodegradable polymers or copolymers, such as poly(lactide-co-glycolide), and a biocompatible, amphipathic copolymer having a water absorption ratio of about 2 or less. A process for the preparation of the novel polymer blends and sustained release compositions comprising the novel polymer blends are also part of the invention described herein. Further the sustained release compositions can be used to deliver a biologically active with a desirable release profile and in a sustained fashion to a patient in need thereof.

REFERENCES:
patent: 4526938 (1985-07-01), Churchill et al.
patent: 4942035 (1990-07-01), Churchill et al.
patent: 5330768 (1994-07-01), Park et al.
patent: 5709852 (1998-01-01), Gopalkrishnan et al.
patent: 5869103 (1999-02-01), Yeh et al.
patent: 5980948 (1999-11-01), Goedemoed et al.
patent: 6117949 (2000-09-01), Rathi et al.
patent: 6201072 (2001-03-01), Rathi et al.
patent: 6296842 (2001-10-01), Jaworowicz et al.
patent: 2214889 (1996-09-01), None
patent: 0 601 799 (1994-06-01), None
patent: WO 93/25583 (1993-12-01), None
patent: WO 95/35097 (1995-12-01), None
patent: WO 01/41735 (2001-06-01), None
Cho, K.Y., et al., “Protein release microparticles based on the blend of poly(D,L-lactic-co-glycolic acid) and oligo-ethylene glycol grafted poly(L-lactide),”Journal of Controlled Release, 76:275-284, (2001).
Lee and Kimura, “Synthesis and properties of poly(L-lactide) including polyether segments,”Kobunshi Ronbun., 52(11):692-697, (1995).
Bittner, B., et al., “Degradation and protein release properties of microspheres prepared from biodegradable poly(lactide-co-glycolide) and ABA triblock copolymers: influence of buffer media on polymer erosion and bovine serum albumin release,”Journal of Controlled Release, 5(60):297-309, (1999).
Bezemer, J.M., et al., “Control of protein delivery from amphiphilic poly(ether ester) multiblock copolymers by varying their water content using emulsification techniques,”Journal of Controlled Release, 66:307-320, (2000).
Morlock, Michael., et al., “Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: protein stabilization and in-vitro release properties,”Journal of Controlled Release, 56:105-115 (1998).

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