Binding domains from Plasmodium vivax and Plasmodium falciparum

Details Binding domains from Plasmodium vivax and Plasmodium falciparum Binding domains from Plasmodium vivax and Plasmodium falciparum

1995-12-07

1998-12-15

Cunningham, Thomas M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

4241851, 4241921, 4242721, 435 693, 435 697, 530350, 530395, A61K 39015, C07K 14445

Patent

active

058493069

ABSTRACT:
The present invention provides isolated polypeptides useful in the treatment and prevention of malaria caused by Plasmodium falciparum or P. vivax. In particular, the polypeptides are derived from the binding domains of the proteins in the EBL family as well as the sialic acid binding protein (SABP) on P. falciparum merozoites. The polypeptides may also be derived from the Duffy antigen binding protein (DABP) on P. vivax merozoites.

REFERENCES:
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