Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2005-04-19
2005-04-19
Badio, Barbara P. (Department: 1616)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C514S170000
Reexamination Certificate
active
06881729
ABSTRACT:
Novel compounds isolated from the bile of male sea lampreys are described, in particular, 7α,12α,24-trihydroxy-5α-cholan-3-one-24-sulfate and 7α,12α-dihydroxy-5α-cholan-3-one-24-oic acid and an ELISA for detecting the compounds. The bile compounds act as pheromones which attract female sea lampreys in water to the point in the water where the compounds had been introduced. The bile compounds are useful in lamprey population management programs where it is desirable to control the locomotion and distribution of lampreys and in food operations where it enhances the efficiency of catching lampreys for food.
REFERENCES:
Bjerselius et al., “Direct behavioral evidence that unique bile acids released by larval sea lamprey (Petromyzon marinus) function as a migratory pheromone.” Can. J. Fish. Aquat. Sci., vol. 57(3), pp. 557-569, Mar. 2000.
Gage Douglas
Li Weiming
Liu Qin
Scott Alexander P.
Siefkes Mike J.
Badio Barbara P.
Board of Trustees of Michigan State University
McLeod Ian C.
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