Bicyclic heterocycles as HIV integrase inhibitors

Details Bicyclic heterocycles as HIV integrase inhibitors Bicyclic heterocycles as HIV integrase inhibitors

2007-02-13

2007-02-13

Berch, Mark L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S552000, C540S362000, C514S210020, C514S230500, C514S080000, C544S105000

Reexamination Certificate

active

11126891

ABSTRACT:
The invention encompasses a series cyclic bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.

REFERENCES:
patent: 2004/0006065 (2004-01-01), Glunz
patent: WO 2003/035076 (2003-05-01), None
patent: WO 2003/035077 (2003-05-01), None
patent: WO 2004/058756 (2004-07-01), None
patent: WO 2004/058757 (2004-07-01), None
patent: WO 2005/061490 (2005-07-01), None
patent: WO 2005/061501 (2005-07-01), None
patent: WO 2006/060731 (2006-06-01), None
patent: WO 2006/103399 (2006-10-01), None
West, Anthony R., Solid State Chemistry and its Applications, Wiley, New York, 1988, pp. 358 & 365.
U.S. Appl. No. 10/755,642, filed Jan. 12, 2004, Michael A. Walker, et al.

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