Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-07-22
2008-07-22
Anderson, Rebecca (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S428000
Reexamination Certificate
active
07402684
ABSTRACT:
The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ:An example is
REFERENCES:
patent: 2005/0043379 (2005-02-01), Axe et al.
patent: EP 0895989 (1999-02-01), None
patent: WO 03/075921 (2004-02-01), None
patent: WO 2004/016609 (2004-02-01), None
Penning, Thomas, “Inhibitors of Leukotriene A4 (LTA4) Hydrolase as Potential Anti-Inflammatory Agents,” Current Pharmaceutical Design, 2001, pp. 163-179.
Penning, Thomas et al., “Synthesis of Imadazophyridines and Purines as Potent Inhibitors of Leukotriene A4 Hydrolase,” Bioorganic & Medicinal Chemistry Letters 13, 2003, pp. 1137-1139.
PCT Search Report based International application No. PCT/2006/024393.
Bedell Louis
Gurney Mark
Mamat Bjorn
Mishra Rama K.
Sandanayaka Vincent
Anderson Rebecca
Bell Charles E.
deCODE genectics ehf.
Hansen Philip E.
Havlin Robert
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