.beta.-methylcarbapenem derivatives, process for the preparation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540302, C07D47714, A61K 3140

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active

058694773

ABSTRACT:
A .beta.-methylcarbapenem compound of formula (I), a salt or an ester thereof, a process for the preparation thereof and a anti-bacterial composition containing same: ##STR1## wherein: R.sup.1 is a C.sub.1-6 alkyl, C.sub.2-6 alkenyl, cycloalkyl, aryl or heterocyclic aryl group.

REFERENCES:
patent: 4429128 (1984-01-01), Rosati
patent: 4479947 (1984-10-01), Christensen
patent: 5064954 (1991-11-01), Uyeo et al.
Schmitt, S.M. et al. Journal of Antibiotics, vol. 41, pp. 780-787 (1988).
Bungaard, H. Design of Prodrugs (Elsevier, Amsterdam), edited by Bungaard, H., pp. 1-6 (1985).

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