.beta.-Lactones of 2-hydroxy-cyclopentane-carboxylic acids

Details .beta.-Lactones of 2-hydroxy-cyclopentane-carboxylic acids .beta.-Lactones of 2-hydroxy-cyclopentane-carboxylic acids

1980-12-15

1981-12-29

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30514

Patent

active

043082092

ABSTRACT:
Novel .beta.-lactones of 2-hydroxy-cyclopentane-carboxylic acids of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen and methyl and R.sub.2 is selected from the group consisting of --CH.sub.2 --O--CH.sub.2 --CH.sub.3 and --X--Ar, X is selected from the group consisting of --O-- and --CH.sub.2 --, Ar is an optionally substituted member selected from the group consisting of thienyl, thiazolyl, phenyl and thiadiazolyl, the optional substituents being at least one member selected from the group consisting of halogen and --CF.sub.3 and the wavy lines indicate that the groups may be in the .alpha.,.beta. or .beta.,.alpha.-positions or mixtures thereof having hypotensive activity and their preparation.

REFERENCES:
patent: 4221809 (1980-09-01), Buendia

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