Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence
Patent
1984-12-14
1986-07-01
Phillips, Delbert R.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
8 to 10 amino acid residues in defined sequence
C07K 716
Patent
active
045979014
ABSTRACT:
2- or 3-.beta.-Indolylalanyl and .beta.-indolylglycyl vasopressins are prepared by standard peptide synthetic methods. These 2- or 3-TRP vasopressins have vasopressin antagonist activity.
REFERENCES:
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patent: 4367225 (1983-01-01), Manning et al.
patent: 4399125 (1983-08-01), Manning et al.
Schroder and Luhke, The Peptides, vol. II, Academic Press, N.Y. 1966 pp. 366-373.
Rittel et al., Experientia, 32(2), 246-248 (1976).
Textbook of Biochemistry, 4th Ed., The MacMillan Co. N.Y., 1966, pp. 1475-1476.
Chemical Abstracts, vol. 83, 67 (1975), Abst. No. 172906e.
Chemical Abstracts, vol. 85, 67 (1976), Abst. No. 57024v.
M. Manning et al., Nature, 308, 652 (1984).
M. Lebl et al., Proceedings of the 17th European Peptide Symposium, 1982.
Edgerton William H.
Lourie Alan D.
Moezie F. T.
Phillips Delbert R.
SmithKline Beckman Corporation
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