.beta.-glucans detection reagents and methods of detecting .beta

Details .beta.-glucans detection reagents and methods of detecting .beta .beta.-glucans detection reagents and methods of detecting .beta

1994-10-12

1996-11-05

Kight, John

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving glucose or galactose

435 4, 435 24, 435 23, 435 29, 435 34, 435 18, 435 13, 4352541, 435963, 436 63, C12Q 154, C12Q 100, C12Q 137, C12N 114

Patent

active

055716830

ABSTRACT:
A .beta.-glucan detection reagent includes a horseshoe crab hemocyte lysate containing an endotoxin neutralizing peptide and a chromogenic substrate. The reagent provides a very sensitive method for detecting .beta.-glucans and is therefore useful as a diagnostic agent such as for detection of nosomycosis.

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Chemical Abstracts vol. 97(3): 19652 p (1981).
Takezawa, J. (1991) Plasma Level of .crclbar.-glucan for Diagnosis and Treatment of Candida SepsisJ. Oshaka Univ. School of Medicine 41:133-142.
Miyata, et al. (1989) Antimicrobial Peptides Isolated From Horseshoe Crab Hemocytes, Tachyplesin II, and Polyphemusins I and II: Chemical Structures and Biological Activity J. Biochem 106:663-668.

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