Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1975-02-18
1977-04-26
Todd, G. Thomas
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
26029354, 260DIG13, C07D22126, A61K 31445
Patent
active
040201643
ABSTRACT:
Benzomorphans of the formula ##STR1## wherein R.sub.1 is H, CH.sub.3 or C.sub.2 H.sub.5 ; R.sub.2 is CH.sub.3 or C.sub.2 H.sub.5 and R.sub.3 and R.sub.4, which can be alike or different, each are lower alkyl, and the acid addition salts thereof with physiologically acceptable acids have CNS activity, including analgesic, morphine antagonistic, anti-convulsive, muscle relaxant, sedative and neuroleptic activity.
REFERENCES:
patent: 3417094 (1968-12-01), Dexter
patent: 3644373 (1972-02-01), Kigasawa et al.
patent: 3723440 (1973-03-01), Freter et al.
Gulati et al., Indian J. Pharm. 27(7), pp. 195-197 (1965); Chem. Abstracts 63:10536a.
Horowski Reinhard
Kehr Wolfgang
Palenschat Dieter
Paschelke Gert
Rahtz Dieter
Schering Aktiengesellschaft
Todd G. Thomas
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