Benzofuran compounds, compositions and methods for treatment...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C549S468000, C549S469000

Reexamination Certificate

active

10699336

ABSTRACT:
The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.

REFERENCES:
patent: 4988727 (1991-01-01), Clemence et al.
patent: 5721233 (1998-02-01), Grisar et al.
patent: 6653346 (2003-11-01), Wang et al.
Ambinter Stock Screening Collection Catalog, Ambinter, Paris, France; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Jan. 1, 2004).
TimTec Microplates Catalog, TimTec, Inc., Newark, DE; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Jan. 19, 2004).
AKos Samples Catalog, AKos Consulting and Solutions, GmbH Basel, Switzerland; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Feb. 9, 2004).
TimTec Stock Library Catalog, TimTec, Inc., Newark, DE; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Jan. 19, 2004).
Interchim Intermediates Catalog, Interchim, Montlucon, France; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Jul. 9, 2002).
ChemBridge Product List, ChemBridge Corp., San Diego, CA; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Jan. 17, 2002).
Screening Collection Catalog, Zelinsky Inst. Of Organic Chemistry, Moscow, Russia; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Aug. 11, 2003).
Chemical Block Stock Library Catalog, Chemical Block, Ltd., Moscow, Russia; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Feb. 2, 2004).
AsInEx Express Gold Collection Catalog, AsInEx, Moscow, Russia; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Apr. 23, 2003).
Interbioscreen Compound Library Catalog, Interbioscreen Ltd., Moscow, Russia; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (May 9, 2003).
Otava Stock Chemicals Catalog, Otava, Kyiv, Ukraine; Chemical Name: 3-Benzofurancarboxamide, 5-methoxy-N-methyl-2-phenyl- (Nov. 26, 2003).
Ambinter Stock Screening Collection Catalog, Ambinter, Paris, France; Chemical Name: 3-Benzofurancarboxamide, 5-hydroxy-N-methyl-2-phenyl- (Jan 1, 2004).
AKos Samples Catalog, AKos Consulting and Solutions GmbH Basel, Switzerland; Chemical Name: 3-Benzofurancarboxamide, 5-hydroxy-N-methyl-2-phenyl- (Feb. 9, 2004).
Interchim Intermediates Catalog, Interchim, Montlucan, France; Chemical Name: 3-Benzofurancarboxamide, 5-hydroxy-N-methyl-2-phenyl- (Jul. 9, 2002).
ChemBridge Product List, ChemBridge Corp., San Diego, CA; Chemical Name: 3-Benzofurancarboxamide, 5-hydroxy-N-methyl-2-phenyl- (Jan. 17, 2002).
Interbioscreen Compound Library Catalog, Interbioscreen Ltd., Moscow, Russia; Chemical Name: 3-Benzofurancarboxamide, 5-hydroxy-N-methyl-2-phenyl- (May 9, 2003).
Otava Stock Chemicals Catalog, Otava, Kyiv, Ukraine; Chemical Name: 3-Benzofurancarboxamide, 5-hydroxy-N-methyl-2-phenyl- (Nov. 26, 2003).
Structural formulas from “Screening Compound Database” of Pharmeks Ltd., Moscow Russia, including Pharmeks ID Nos. PHAR000844 (Mol. Formula C24H18BrNO6), PHAR023049 (Mol. Formula C23H23BrO5) and PHAR023900 (Mol. Formula C18H15BrO5) (1page); Sep. 2002.

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