Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-04-24
2007-04-24
Lambkin, Deborah C. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S320000, C544S376000, C546S196000
Reexamination Certificate
active
10481367
ABSTRACT:
A compound represented by the formula:(wherein, R1and R2are the same or different and each represents a hydrogen atom, hydrocarbon group or heterocyclic group, or R1and R2may form, together with the adjacent carbon atom, a 3–8 membered iso- or heterocyclic group, R3represents a cyclic group, a hydroxy group, a mercapto group that may have oxo, or an amino group, R4represents a hydrogen atom, a hydrocarbon group, a hydroxy group, a mercapto group which may have oxo, or an amino group, or R2and R4may link together to form a double bond, X represents a bond or a linear hydrocarbon group, W represents an oxygen atom or a sulfur atom, ring B represents a 5–8 membered nitrogen-containing heterocyclic group, ring C represents a benzene ring, and— represents a single bond or a double bond), or a salt or a prodrug thereof that has excellent neurodegenerative inhibitory activity and brain penetrability, and is useful as an agent for preventing/treating neurodegenerative diseases.
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Miyamoto Masaomi
Ohkawa Shigenori
Okura Masahiro
Tsukamoto Tetsuya
Chao Mark
Lambkin Deborah C.
Ramesh Elaine M.
Takeda Pharmaceutical Company Limited
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