Benzo (f) insoindol derivatives and their use as ep4...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S215000, C548S243000, C548S416000, C548S427000, C548S450000, C546S276700, C514S374000, C514S378000, C514S411000

Reexamination Certificate

active

10450639

ABSTRACT:
Compounds of formula (I)and pharmaceutically acceptable derivatives thereof bind with high affinity to the EP4 receptor and are of use in the treatment or prevention of conditions such as a pain, inflammatory, immunological, bone, neurodegenerative or renal disorder.

REFERENCES:
patent: 6018068 (2000-01-01), Nagao et al.
patent: 6861441 (2005-03-01), Clayton et al.
patent: 6924297 (2005-08-01), Giblin et al.
patent: 0 845 451 (1988-06-01), None
patent: WO 00/18744 (2000-04-01), None

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