Benzimidazole derivatives useful as histamine H3 antagonists

Details Benzimidazole derivatives useful as histamine H3 antagonists Benzimidazole derivatives useful as histamine H3 antagonists

2006-09-12

2006-09-12

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S224000, C544S336000, C546S184000, C546S192000, C546S193000, C546S194000

Reexamination Certificate

active

07105505

ABSTRACT:
Disclosed are novel compounds of the formulawherein R1is optionally substituted benzimidazolyl or a derivative thereof; R2is optionally substituted aryl or heteroaryl; M1and M2are C(R3) or N; and the remaining variables are as defined in the specification; also disclosed are pharmaceutical compositions comprising the compounds of formula I and methods of treating various diseases or conditions, such as allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of formula I, as well as methods of treating said diseases or conditions using the compounds of formula I in combination with an H1receptor antagonist.

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