Benzimidazole compound

Details Benzimidazole compound Benzimidazole compound

2006-09-14

2008-09-16

Morris, Patricia L (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07425634

ABSTRACT:
An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability.Provided is a compound represented bywhere R1and R3may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group;R4, R5, R6and R7represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1represents a single bond, methylene or ethylene group,a salt thereof or a solvate of these.

REFERENCES:
patent: 4808596 (1989-02-01), Matsuishi et al.
patent: 5039806 (1991-08-01), Brändsträm et al.
patent: 5430042 (1995-07-01), Lindberg et al.
patent: 2004/0266828 (2004-12-01), Garvey et al.
patent: 0 187 977 (1986-07-01), None
patent: 0 254 588 (1988-01-01), None
patent: 59-181277 (1984-10-01), None
patent: 62-207271 (1987-09-01), None
patent: 63-146882 (1988-06-01), None
patent: 1-190682 (1989-07-01), None
patent: 2-22273 (1990-01-01), None
patent: 5-177268 (1993-05-01), None
patent: 5-507713 (1993-11-01), None
patent: WO-91/19712 (1991-12-01), None
patent: WO-00/50037 (2000-08-01), None
patent: WO-2004/035020 (2004-04-01), None
Vippagunta et al., “Crystalline Solids”, Advanced Drug Delivery Reviews, 48 (2001), 3-26.
Guiillory “Generation of, etc.,” in Brittain (ed.), Polymorphism in Pharmaceutical Solids, 95, Marcel Dekker, NY, 1999, 183-226.
N.J.V. Bell et al.; Appropriate Acid Suppression for the Management of Gastro-Oesophageal Reflux Diease; Digestion 1992; 51(supp 1): 59-67.
Matsuishi et al. II, “Preparation of, etc.”, CA 112:77192 (1990).
Abstract: JP 62-207271, Sep. 11, 1987.

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