(Benzhydryloxyethylpiperidyl) aliphatic acid derivatives and the

Details (Benzhydryloxyethylpiperidyl) aliphatic acid derivatives and the (Benzhydryloxyethylpiperidyl) aliphatic acid derivatives and the

1992-12-22

1994-03-15

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546232, 546235, 546239, A01N 4102, C07D21118

Patent

active

052946231

ABSTRACT:
Compounds of formula (I): ##STR1## in which: R.sup.1 and R.sup.2 are independently alkyl, alkoxy, trifluoromethyl, nitro or halogen; A is an aliphatic hydrocarbon group having from 2 to 8 carbon atoms whose chain contains at least 2 carbon atoms in a linear chain between the piperidine group and --COOH, said group optionally being unsaturated; and m and n are independently 0, 1, 2 or 3; and pharmaceutically acceptable salts and esters thereof have been found to have valuable anti-histamine properties without the usual side effects of anti-histamines. Methods of preparing the compounds are also provided.

REFERENCES:
patent: 2567351 (1961-09-01), Rieveschl
patent: 4957927 (1990-09-01), Ferrand et al.

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