Benzamide protease inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546162, 546306, 544329, 544332, 544326, 544409, 548128, 548139, 548185, 548195, 548233, 548329, 548337, 548483, C07D21516, C07D23902, C07D28508, C07D26348

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active

048748641

ABSTRACT:
Compounds of the formula ##STR1## where HET is a heterocyclic group, n is an integer of 0 to 2 and R.sup.1 is hydrogen or lower alkyl are protease inhibitors use as anti-plasmin and anti-thrombin agents.

REFERENCES:
patent: 4563527 (1986-01-01), Fujii et al.
patent: 4732916 (1988-03-01), Satoh et al.
Dubey et al., Chem. Abstracts, vol. 104; 148706w (1986).

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