Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-12-13
2005-12-13
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S231500, C544S182000, C544S112000
Reexamination Certificate
active
06974812
ABSTRACT:
The present invention provides benzamide inhibitors of the P2X7receptor of the formula:wherein R1-R3are as defined herein. The compounds of the invention are useful in the treatment of IL-1 mediated disorders, including, without limitation, inflammatory diseases such as osteoarthritis and rheumatoid arthritis; allergies, asthma, COPD, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
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“Benzamide Inhibitors of the P2X7 Receptor” U.S. Appl. No. 10/748,342, Filed Dec. 30, 2003.
Dombroski Mark A
Duplantier Allen J.
Ancona Pamela C.
Balasubramanian Venkataraman
Baude Eric J.
Eck Steven R.
Pfizer Inc.
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