Benzamide derivatives and pharmaceutical compositions...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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C514S352000, C514S277000, C514S247000, C546S342000, C546S290000, C544S238000, C544S242000, C544S336000, C549S030000, C549S049000, C549S200000, C549S302000, C548S400000, C548S452000, C564S342000

Reissue Patent

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10640278

ABSTRACT:
The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.

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M. Clark et al, “Validation of the General Purpose Tripos 5.2 Force Field”,Journal of Computational Chemistry,vol. 10, No. 8, 1989, pp.982-1012.

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