Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1996-03-15
1998-06-23
Ketter, James
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530350, 530329, C07K 1400, C07K 700
Patent
active
057706905
ABSTRACT:
Bax-.omega. polynucleotides and polypeptides, and compositions effective to hybridize to Bax-.omega. polynucleotides are disclosed. Also disclosed are methods for altering apoptosis in cells, for promoting cell survival and for identifying compounds capable of affecting the binding of Bax-.omega. to other proteins involved in apoptosis.
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Bitler Catherine Mastroni
Bowersox Stephen Scott
Crea Roberto
Demo Susan Dunham
Horne William A.
Dehlinger Peter J.
Ketter James
Neurex Corporation
Sholtz Charles K.
Yucel Irem
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