Basic non-peptide bradykinin antagonists and pharmaceutical...

Details Basic non-peptide bradykinin antagonists and pharmaceutical... Basic non-peptide bradykinin antagonists and pharmaceutical...

2003-06-05

2009-02-17

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S311000, C514S314000

Reexamination Certificate

active

07491825

ABSTRACT:
Non-peptide compounds of formula (I) having activity as specific antagonists of bradykinin (BK) B2 receptor. The compounds are chemically characterized by the presence of an alpha, alpha-disubstituted amino acid at least one amino group, free or salified, or the corresponding ammonium quaternary salt. These BK receptor antagonists are a novel class of medicaments which can be used in all the disorders in which the receptors are involved.

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