Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1993-02-22
1994-01-04
Naff, David M.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 93D, 424 93K, 4352525, 435832, A01N 6300, A61K 3700, C12N 120
Patent
active
052758150
ABSTRACT:
Disclosed and claimed is a novel Bacillus thuringiensis isolate designated B.t. NRRL B-18721 which has activity against dipteran insect pests. Thus, this isolate, or mutants thereof, can be used to control such insect pests. Further, genes encoding novel .delta.-endotoxins can be removed from the isolate and transferred to other host microbes, or plants. Expression of the .delta.-endotoxins in such hosts results in the control of susceptible insect pests in the environment of such hosts.
REFERENCES:
patent: 4918006 (1990-04-01), Ellar et al.
patent: 4945057 (1990-07-01), Temeyer et al.
Couch, T. L. (1980) "Mosquito Pathogenicity of Bacillus thuringiensis var. israelensis," Developements in Industrial Microbiology 22:61-67.
Beegle, C. C. (1978) "Use of Entomogenous Bacterial in Agroecosystems," Developments in Industrial Microbiology 20:97-104.
Goldberg, L. J., J. Margalit (1977) "A Bacterial Spore Demonstrating Rapid Larvicidal Activity Against Anopheles sergentii, Uranotaenia unguiculata, Culex univitattus, Aedes aegypti, and Culex pipiens, " Mosquito News 37:355-358.
Pauda, L. L., M. Ohba, K. Aizawa (1984) "Isolation of a Bacillus thuringiensis Strain (Serotype 8a:8b) Highly and Selectively Toxic against Mosquito Larvae," Journal of Invertebrate Pathology 44:12-17.
Mulla, M. S., B. A. Federici, H. A. Darwazeh (1982) "Larvacidal Efficacy of Bacillus thuringiensis Serotype H-14 Against Stagnant-Water Mosquitoes and Its Effects on Nontarget Organisms," Environ. Entomol. 11:788-795.
Temeyer, K. B. (1990) "Potential of Bacillus thuringiensis for Fly Control," Fifth International Colloquium on Invertebrate Pathology and Microbial Control, Society for Invertebrate Pathology, pp. 352-356.
Lankford L. Blaine
Mycogen Corporation
Naff David M.
LandOfFree
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