Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-08-29
1999-11-30
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514194, 514195, 514196, 514197, 514198, 514200, 514201, 514202, 514203, 514204, 514205, 514206, 514207, 514208, 514209, 514210, 540355, A61K 31545, A61K 3143, C07D205085, C07D40912
Patent
active
059943408
ABSTRACT:
New 2-oxo-1-azetidine sulfonic acid derivatives with an aminoalkyl substituted "anti" (E-isomer) oxyimino group in the acylamino substituent at the 3 position of the monobactam ring. These compounds are potent inhibitors of bacterial .beta.-lactamases. These compounds can be used in combination with .beta.-lactam antibiotics to increase the effectiveness of the .beta.-lactam antibiotics in fighting infection caused by .beta.-lactamase producing bacteria.
REFERENCES:
patent: 4816582 (1989-03-01), Furlenmeier
patent: 4900728 (1990-02-01), Heymes
White and Handler, "The Proteins" 6th edition, p. 77, 1992.
Higashitani Fusahiro
Kunugita Chieko
Maiti Samarendra N.
Micetich Ronald G.
Nishida Koichi
Berch Mark L.
SynPhar Laboratories, Inc.
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