Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1996-09-16
1999-10-26
Wax, Robert A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, 435194, 4352523, 4353201, 536 231, 536 232, 536 2431, 536 2433, C12Q 168, C12P 1934, C12N 912, C07H 2104
Patent
active
059726059
ABSTRACT:
Telomerase reporter constructs suitable for use in reporting transcriptional activity of a mammalian telomerase gene transcription regulatory region contain a transcription regulatory region of a mammalian telomerase gene operably linked to a reporter polynucleotide sequence.
REFERENCES:
patent: 5583016 (1996-12-01), Villeponteau et al.
patent: 5645986 (1997-07-01), West et al.
Feng, et al., "The RNA Component of Human Telomerase", Science, 269:1236 (1995).
Kim, et al., "Specific Association of Human Telomerase Activity with Immortal Cells and Cancer", Science, 266:2011 (1994).
Grider, et al., "Telomeres, Telomerase and Cancer", Scientific American, Feb. 1996, pp. 92-97.
Harley, et al., "Telomeres and telomerase in aging and cancer", Current Opinion in Genetics and Development, 5:249-255 (1995).
Harley, "Telomeres and Aging: Fact, Fancy, And The Future", The Journal of NIH Research, 7:64-68 (1995).
Villeponteau, "The RNA components of human and mouse telomerases", Cell & Developmental Biology, 7:15-21 (1996).
Harley Calvin
Villeponteau Bryant
Geron Corporation
Saidha Tekchand
Wax Robert A.
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