Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1995-06-02
1996-12-31
Knode, Marian C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303911, 5303913, 435 74, 435 792, 435 794, 435 795, 435 21, 435975, 436518, 436548, 436808, C07K 1640
Patent
active
055895743
ABSTRACT:
Monoclonal antibodies highly specific for human bone alkaline phosphatase, especially in the presence of human liver alkaline phosphatase, and their use in assays for human bone alkaline phosphatase are disclosed. A kit using the antibodies in an assay for human bone alkaline phosphatase is also disclosed.
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Bailyes et al., "The Preparation Of Monoclonal Antibodies To Human Bone and Liver Alkaline Phosphatase And Their Use In Immunoaffinity Purification And In Studying These Enzyme When Present In Serum" Biochemistry Journal vol. 244:725-733 (1987).
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Seabrook et al., "The Distinction Of Bone And Liver Isoenzyme Of Alkaline Phosphatase In Serum Using A Monoclonal Antibody" Clinica Chimica Acta. 172:261-266 (1988).
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Hill Craig S.
Wolfert Robert L.
Hampson Gary T.
Hybritech Incorporated
Kivinski Margaret A.
Knode Marian C.
May William H.
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