Assay based on doped nanoparticles

Details Assay based on doped nanoparticles Assay based on doped nanoparticles

2002-11-04

2008-08-12

Lam, Ann Y (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

Reexamination Certificate

active

07410810

ABSTRACT:
The invention relates to an assay based on resonance energy transfer (RET), comprising a first molecule grope A, which is marked with at least one energy donor, and at least one second molecule group B which is marked with at least one energy acceptor, the donor comprising a molecule or particle which can be energetically excited by an external radiation source and which is fluorescence enabled and the acceptor comprising a molecule or particle which can be excited by energy transfer via the donor with partial or complete quenching of the donor fluorescence, and the donor and/or acceptor comprise luminescing inorganic dope nanoparticles having an expansion of ≦50 nanometers, emitting electromagnetic radiation with stokes or anti-stokes scattering after energetic excitation.

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