Aspartylamide derivatives and sweeteners

Details Aspartylamide derivatives and sweeteners Aspartylamide derivatives and sweeteners

1997-01-13

2000-01-04

Barts, Samuel

Food or edible material: processes, compositions, and products

Products per se, or processes of preparing or treating...

Noncarbohydrate sweetener or composition containing same

562448, 562508, 562564, A23L 1236

Patent

active

060107332

ABSTRACT:
Novel aspartylamide derivatives such as N-(.alpha.-L-aspartyl-(1R,2S,4S)-1-methyl-2-hydroxy-4-phenylhexylamide, N-.alpha.-7(N'-3,3-dimethylbutylaspartyl)-(1R,2S,4S)-1-methyl-2-hydroxy-4- phenylhexylamide) and the like, and a sweetener containing the above-mentioned derivatives or salts thereof as an active ingredient, is low-calory and which exhibits a high level of stability, an excellent safety and an excellent sweetness.

REFERENCES:
patent: 3803223 (1974-04-01), Mazur et al.
patent: 4423029 (1983-12-01), Rizzi
Journal of Medicinal Chemistry, vol. 13, No. 6, pp. 1217-1221, (1970), Robert H. Mazur, et al., "Structure-Taste Relationships of Aspartic Acid Amides".
Tetrahedron Letters, vol. 35, No. 37, pp. 6891-6894, (1994), Yashifumi Yuasa, et al., "The Sweetness and Stereochemistry of L-Aspartyl-Fenchylaminoalcohol Derivatives".

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