Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-01-11
2011-01-11
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S242000, C514S265100, C544S183000, C544S280000, C540S568000
Reexamination Certificate
active
07868000
ABSTRACT:
Disclosed are compounds of the formula Ior a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein j, k, U, W, R, R1, R2, R3, R4, R6, R7and R7aare as described above in the specification.Also disclosed is the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic m1agonist or m2antagonist.
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Now
Greenlee William J.
Liu Xiaoxiang
Mandal Mihirbaran
McKittrick Brian
Stamford Andrew
Devlin Gerard M.
Lee William Y.
MacMillan Keith D.
Murray Jeffrey H
Schering Corporation
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