Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-03-25
1995-11-14
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142268, 5142288, 514326, 514372, 514374, 514385, 514399, 540598, 540601, 540603, 544 54, 544 96, 544335, 546209, 546210, 548146, 548238, 5483147, A61K 3155, A61K 3154, C07D40510, C07D27906
Patent
active
054666872
ABSTRACT:
The invention relates to arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes of the general formula ##STR1## (wherein n, m, p, A, W.sup.1, W.sup.2, X, Y, and R.sup.1 to R.sup.11 are as defined in claim 1) and the isomers, isomer mixtures and salts thereof, which have useful properties, in particular an inhibitory effect on cholesterol biosynthesis.
REFERENCES:
patent: 4863932 (1989-09-01), Sinensky
patent: 5169844 (1992-12-01), Commons et al.
patent: 5187271 (1993-02-01), Bovy et al.
H. Buchwald, "Cholesterol inhibition, cancer, and chemotheraphy", vol. 339, May 9, 1992, 1154-1156.
The Merck Index, Eleventh Edition, 1989, 878-879, 1351-1352.
Budzinski Ralph-Michael
Eisele Bernhard
Hallermayer Gerhard
Hurnaus Rudolf
Maier Roland
Devlin Mary-Ellen M.
Dr. Karl Thomae GmbH
Grumbling Matthew V.
Raymond Robert P.
Shah Mukund J.
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