Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, th

Details Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, th Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, th

1994-03-25

1995-11-14

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142268, 5142288, 514326, 514372, 514374, 514385, 514399, 540598, 540601, 540603, 544 54, 544 96, 544335, 546209, 546210, 548146, 548238, 5483147, A61K 3155, A61K 3154, C07D40510, C07D27906

Patent

active

054666872

ABSTRACT:
The invention relates to arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes of the general formula ##STR1## (wherein n, m, p, A, W.sup.1, W.sup.2, X, Y, and R.sup.1 to R.sup.11 are as defined in claim 1) and the isomers, isomer mixtures and salts thereof, which have useful properties, in particular an inhibitory effect on cholesterol biosynthesis.

REFERENCES:
patent: 4863932 (1989-09-01), Sinensky
patent: 5169844 (1992-12-01), Commons et al.
patent: 5187271 (1993-02-01), Bovy et al.
H. Buchwald, "Cholesterol inhibition, cancer, and chemotheraphy", vol. 339, May 9, 1992, 1154-1156.
The Merck Index, Eleventh Edition, 1989, 878-879, 1351-1352.

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