Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2006-08-29
2006-08-29
Owens, Amelia A. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
active
07098247
ABSTRACT:
The present invention describes compounds of the general formula Ias well as processes for their manufacture, pharmaceutical compositions containing them and methods for using these compounds and pharmaceutical compositions as pharmaceutical agents. The compounds according to this invention show antiproliferative and differentiation-inducing activity, which results in inhibition of tumor cell proliferation, induction of apoptosis and inhibition of invasion.
REFERENCES:
patent: 3810910 (1974-05-01), Meyer et al.
patent: 5137918 (1992-08-01), Weiershausen et al.
patent: 2062265 (1972-05-01), None
patent: 0242851 (1987-10-01), None
patent: 0847992 (1998-06-01), None
patent: 2167954 (1973-08-01), None
Lu, Qiang et al ‘Zn2+ chelating motif-tethered short-chain fatty acids as novel class of histone deacetylase inhibitors’ J. Med. Chem. 2004, 47, 467-474.
Hassan, H. et al., Indian J. Chem. 39B, 2000, p. 764-768.
Koyama, Y. et al., Blood 96, 2000, p. 1490-1495.
Millot, N. et al., Synthesis 7, 2000, p. 941-948.
Moll, R. et al., Z. Chem. 17, 1977, p. 133-134.
Rastogi, R. and Sharma, S., Indian J. Chem., Sect. B, 21B, 1982, p. 485-487.
Vorbruegghen, H. and Krolikeiewicz, Synthesis 4, 1983, p. 316-319.
Fertig Georg
Herting Frank
Koerner Matthias
Kubbies Manfred
Limberg Anja
Hoffmann-La Roche Inc.
Johnston George W.
Owens Amelia A.
Remy Brian C.
Rocha-Tramaloni Patricia S.
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