Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1999-02-16
2000-09-26
Chin, Christopher L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 75, 435 6, 422 50, 422 8205, 422 8206, 422119, 422 8211, 4241781, 4241791, 424484, 424489, 424502, 436518, 436524, 436527, 436528, 436531, 436532, 436533, 436 63, 436 71, 436 86, 436823, 436829, 436 56, 250304, 250330, 2503381, 2503382, 25033914, 2503541, G01N 3353, G01N 2129, G01N 33558, G01N 33543, G61K 39395, G61K 914, G01D 1126, G01F 101
Patent
active
061241032
ABSTRACT:
An arrangement for the investigation of hydrophilic macromolecules (1) in an aqueous solution having a solid carrier surface (5) onto which a lipid film (24) is disposed, wherein the molecules (1) to be investigated are bound, by means of a molecular coupling system (20), to the lipid film (24) and thus are immobilized, is characterized in that the molecular coupling system (20) comprises at least two, preferably three molecular or nuclear components (21, 22, 23), which can be coupled to each other, of which a first component (21) is bound to the lipid film (24) and a second component (22) is bound to a hydrophilic macromolecule (1) to be investigated. In this way, it is rendered possible to immobilize and investigate any hydrophilic macromolecules, wherein the coating of the solid carrier surface should be able to be carried out in an as easy as possible and reversible manner.
REFERENCES:
patent: Re34312 (1993-07-01), Geiger et al.
patent: 4175864 (1979-11-01), Gilby
patent: 4348329 (1982-09-01), Chapman
patent: 4670386 (1987-06-01), Sugaar
patent: 4752572 (1988-06-01), Sundberg et al.
patent: 4874710 (1989-10-01), Piran
patent: 4880731 (1989-11-01), Kaspar
patent: 4933114 (1990-06-01), O'Brien et al.
patent: 4935339 (1990-06-01), Zahradnik
patent: 4959303 (1990-09-01), Milburn et al.
patent: 4966839 (1990-10-01), Kaspar
patent: 4975581 (1990-12-01), Robinson et al.
patent: 5000960 (1991-03-01), Wallach
patent: 5093580 (1992-03-01), Sting
patent: 5097129 (1992-03-01), De Vries et al.
patent: 5126241 (1992-06-01), Schenk
patent: 5229611 (1993-07-01), Ukon
patent: 5234812 (1993-08-01), Buck et al.
patent: 5527711 (1996-06-01), Tom-Moy et al.
patent: 5553616 (1996-09-01), Ham et al.
patent: 5567591 (1996-10-01), Lovell et al.
patent: 5622872 (1997-04-01), Ribi
patent: 5643731 (1997-07-01), Bosslet et al.
patent: 5694930 (1997-12-01), Pries et al.
patent: 5729018 (1998-03-01), Wells et al.
patent: 5746217 (1998-05-01), Erickson et al.
patent: 5754715 (1998-05-01), Melling
patent: 5754722 (1998-05-01), Melling
patent: 5866430 (1999-09-01), Grow
patent: 5945674 (1999-08-01), Dukor
Biophys. J. 1991, Columw 59, pp. 387-396: Darst et al.: "Two-dimensional crystal of streptavidin on . . . ".
Current Opinion in Structural Biology, 1991, 1(4) pp. 642-646: Kronberg et al.: "Two-dimensional crystals of proteins on lipid layers".
Bruker Analytik GmbH
Chin Christopher L.
Do Pensee T.
Vincent Paul
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