Aqueous solution of olanexidine, method of preparing the...

Cleaning compositions for solid surfaces – auxiliary compositions – Cleaning compositions or processes of preparing – With halogen – nitrogen – oxygen – or phosphorus containing...

Reexamination Certificate

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C510S488000, C510S499000, C510S506000, C422S028000

Reexamination Certificate

active

07825080

ABSTRACT:
The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution that contains olanexidine and at least an equimolar amount of gluconic acid, and substantially contains neither an acid other than gluconic acid nor a salt of the acid other than gluconic acid.

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Supervised by Suzuki et al, pp. C-1225 to C-1229 (2001).
Edited by Japan Pharmaceutical Excipients Council, Iyakuhin Tenkabutsu Jiten, Kabushiki Kaisha Yakuji Nipposha, pp. 119-121, 126-129 (1994).
Umehara K. et al., “In Vitro Characterization of the Oxidative Cleavage of the Octyl Side Chain of Olanexidine, A Novel Antimcrobial Agent, in Dog Liver Microsomes”, vol. 28, No. 12, 2000, pp. 1417-1424 (XP002451421).
European Search Report dated Oct. 9, 2007.
European Office Action dated Nov. 24, 2008.
Chinese Office Action dated Dec. 8, 2006.

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