Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1989-06-28
1991-03-19
Rose, Shep A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
A61K 3121
Patent
active
050011510
ABSTRACT:
Nitroglycerin injection that is free of the customary organic solvents and has an extended shelf life of at least 1 year, consisting essentially of water, lactose, and nitroglycerin. Sodium chloride or dextrose may be added during manufacture or upon diluting with an infusion. Commercially safe manufacture and stable dispersion are assured by mixing lactose adsorbate, containing nitroglycerin, with water at high shear so that no nitroglycerin droplets coalesce. Stability is maintained by filtering and filling operations using nonreactive, nonleaching, nonadsorptive materials.
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Burghart C. A. 101:60147s (1984).
Scheife et al. 1-A. 96:74582v (1982).
Stratulat et al. GA. 99:93749h (1983).
Alam Abu S.
Joshi Utpal G.
Kapoor John N.
Mehta Jairaj U.
Sayeed Fakrul A. A.
Drehkoff W. Dennis
Fujisawa USA, Inc.
Rose Shep A.
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