Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Skin cosmetic coating
Patent
1990-05-09
1993-03-16
Page, T. K.
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Skin cosmetic coating
424401, 424402, 424484, 424485, 424487, 424488, 5147726, 514777, 514781, 514782, 514844, 514944, 523105, A61K 702, A61K 748, A61K 3710, A61K 31725
Patent
active
051942534
DESCRIPTION:
BRIEF SUMMARY
The invention relates to a novel aqueous gel based on hyaluronic acid and on highly polymerised deoxyribonucleic acid, a process for its preparation, and also its use in cosmetics for the preparation of a skin treatment mask.
Hyaluronic acid is a high molecular weight polysaccharide which forms an important component of the extracellular matrix of conjunctive tissues, in particular in the skin, the tendons, the cartilages and the muscles. Hyaluronic acid may for example be obtained in the form of its sodium salt by extraction from cockscomb, and its industrial production by bacterial fermentation is envisaged. It displays a very great capability for retention of water in the form of a solution or of a gel having pseudo-plastic properties and a visco-elastic flow.
Hyaluronic acid and its salts, in particular its sodium salt, are used in cosmetic products having a beneficial effect on the skin, in particular due to the fact that aqueous solutions of hyaluronic acid have an excellent hydrating effect.
Elsewhere, it has been proposed to use reticulated gels based on hyaluronic acid to hold a substance having a biological or pharmacological activity and to progressively liberate this substance, in a controlled manner, on contact with the skin. Such reticulated gels and their use are, for example, described in the patent FR-A-2,574,414.
The patent application JP-A-59.134706 describes a composition for hydration of the skin, containing nucleic acids, a hydrating agent such as hyaluronic acid, and various active constituents. A gel intended for the preparation of a cosmetic mask, comprising an alginate, a salt of a bivalent metal, a phosphate, an anionic surface-active agent and a filler such as SiO.sub.2, ZnO, Al.sub.2 O.sub.3, etc., is described in the patent application EP-A-0045493.
It is an object of the present invention to provide a homogeneous aqueous gel comprising on the one hand hyaluronic acid, and on the other hand another substance capable of effecting a beneficial action on the skin, in the form of an aqueous gel, this gel being in an appropriate form for its application to the skin, more particularly as a cosmetic treatment mask, and having the property of being able to be very rapidly hardened, at least on the surface, in such a way as to produce a coherent film by a process which is simple and easy to regulate, without giving off heat or liberating or bringing into play a toxic substance.
Accordingly, the aqueous gel according to the invention is characterised in that it is essentially formed of a homogeneous mix of an aqueous gel; weight in the form of an aqueous gel; film-forming gels.
The expression "having the property of forming aqueous film-forming gels" refers to a hydrophilic polymer capable of forming a non-reticulated gel or an aqueous solution having pseudo-plastic properties, it being possible for this gel or this solution to be easily and rapidly transformed into a coherent plastic film by any appropriate process, for example by insolubilisation or reticulation.
According to a preferred embodiment of the invention, it is advantageous to use as a hydrophilic polymer having the property of forming aqueous film-forming gels, an alginate of an alkali metal or an ammonium alginate, and preferably a sodium alginate. The sodium alginate also has the advantage of being haemostatic and of encouraging the healing of wounds or cuts in the skin, which improves the properties of the gel of the invention.
It is also preferable, according to the present invention, to use as a salt of hyaluronic acid, an alkaline salt such as sodium hyaluronate and, as a salt of deoxyribonucleic acid, a sodium salt, a calcium salt, a magnesium salt, a manganese salt, a lysine salt, or an arginine salt, and more particularly a sodium salt. It is important, according to the present invention, that the deoxyribonucleic acid, in the salt form, be highly polymerised.
The highly polymerised deoxyribonucleic acid, or high molecular weight deoxyribonucleic acid, is a commercially available product obtained from germinative
REFERENCES:
patent: 4178361 (1979-12-01), Cohen et al.
patent: 4707354 (1987-11-01), Garlen et al.
patent: 4965071 (1990-10-01), Kawan
Page T. K.
Pier Auge (Societe Anonyme)
Webman E. J.
LandOfFree
Aqueous gel, usable in cosmetics, based on hyaluronic acid and d does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aqueous gel, usable in cosmetics, based on hyaluronic acid and d, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aqueous gel, usable in cosmetics, based on hyaluronic acid and d will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-349982