Chemical apparatus and process disinfecting – deodorizing – preser – Control element responsive to a sensed operating condition
Reexamination Certificate
2005-09-06
2005-09-06
Walker, W. L. (Department: 1723)
Chemical apparatus and process disinfecting, deodorizing, preser
Control element responsive to a sensed operating condition
C422S105000, C210S321600, C210S321750, C435S305200, C435S305300, C435S305400
Reexamination Certificate
active
06939515
ABSTRACT:
The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymorphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system. Another apparatus may filter the synthesized solution to provide a substantially pure mixture that can be subjected to salt or polymorph testing. Yet another apparatus may be used to crystallize mixtures on a substrate such that the crystallized mixture can be screened by one or more screening devices.
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Carlson Eric D.
Chandler, Jr. William H.
Cong Peijun
Desrosiers Peter J.
Freitag J. Christopher
Memon Krishanan S
Symyx Technologies Inc.
Walker W. L.
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