Apparatus for parallelized two-photon fluorescence correlation s

Details Apparatus for parallelized two-photon fluorescence correlation s Apparatus for parallelized two-photon fluorescence correlation s

1996-08-21

1998-09-29

Hantis, K.

Optics: measuring and testing

By dispersed light spectroscopy

With sample excitation

2504581, 2504591, G01J 330

Patent

active

058152628

ABSTRACT:
An apparatus for carrying out laser-induced two-photon fluorescence correlation spectroscopy (TPA-FCS), in which a plurality of volumes (6) are delimited or defined in the apparatus in such a way that samples (3) introduced into these volumes can be excited and observed in parallel by means of a single laser (1). Such an apparatus is e.g. used to screen active compounds.

REFERENCES:
patent: 5034613 (1991-07-01), Denk et al.
patent: 5043584 (1991-08-01), Koishi
patent: 5051162 (1991-09-01), Kambara et al.
Madge et al., Phys. Rev. Lett., vol. 29, 1972, pp. 705-708.
Rigler et al., Phys. Scr., vol. 19, 1979, pp. 486-490.
Thompson, Topics in Fluorescence Spectoscopy, vol. 1, 1991, pp. 337-410.
Berland et al., Biophys. J., vol. 68, 1995, pp. 694-701.
T. Wilson, Confocal Microscopy, Academic Press, London, 1984, pp. 1-64.

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