Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Sample mechanical transport means in or for automated...
Patent
1977-10-28
1980-11-18
Serwin, R. E.
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Sample mechanical transport means in or for automated...
250208, 356246, 356435, 356222, 422 67, G01N 2124, G01N 114
Patent
active
042345383
ABSTRACT:
Apparatus for measuring progressively the absorbance changes of a large number of aliquots from a plurality of different samples. The sample introduction, testing instructions, aliquot preparation, reagent dispensing, absorbance measuring and data recording all can be accomplished in a continuous mode of processing. Stat and batch operation also can be accomplished. The aliquots are in an array of cuvettes which is advanced slowly along a circular path. Photometer means, preferably having several photometric detectors, are mounted in fixed orientation on a common support that advances rapidly along a similar circular path, such that radiation passing through each of the cuvettes is monitored many times by a specific photometric detector by the time that that cuvette completes one circuit of its path. The photometric detectors can operate at several different wavelengths. Many different chemical reactions can be monitored at the same time. The radiant energy passing through each cuvette is received by the continuously moving photometer means, is converted electrically into a digitized value proportional to absorbance and is transmitted digitally from the moving assemblage of photometric detectors, cuvettes and electrical components to a stationary receiver. In one embodiment, the digital transmission is in the form of a pulsed train of light signals. In another embodiment, one or more slip rings transmit electric signals from the moving assemblage to the stationary portion. Suitable drive elements, sample and reagent storage and transfer mechanisms as well as cuvette laundry means may be provided as part of the complete apparatus.
REFERENCES:
patent: 3504981 (1970-04-01), Malvin
patent: 3554654 (1971-01-01), Paatzsch et al.
patent: 3567393 (1971-03-01), Welch
patent: 3748044 (1973-07-01), Liston
patent: 3873273 (1975-03-01), Moran et al.
patent: 4007011 (1977-02-01), Greaves et al.
Anderson, Analytical Biochemistry, 28, 545-562, (1969).
Ginsberg Guenter
Horne Thomas
Kreiselman Robert L.
Coulter Electronics Inc.
Serwin R. E.
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