Apparatus for detecting biomolecular bonding and a method...

Details Apparatus for detecting biomolecular bonding and a method... Apparatus for detecting biomolecular bonding and a method...

2006-01-03

2009-06-09

Forman, BJ (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S283100, C435S287200, C435S288700, C422S064000, C422S068100, C422S082050

Reexamination Certificate

active

07544472

ABSTRACT:
An apparatus and method for detecting biomolecular bonding are disclosed. The apparatus comprises a substrate; a rotation unit mounted on the substrate, a probe biomolecule immobilized on a surface of the rotation unit; an input port and an output port connected with the substrate. A frequency detector is connected with the output port to measure rotational frequency of the rotation unit. The presence or absence of molecular bonding is detected by measuring difference between the rotational frequencies before and after mixing the probe biomolecule with a sample biomolecule.

REFERENCES:
patent: 5413939 (1995-05-01), Gustafson et al.
patent: 6319468 (2001-11-01), Sheppard et al.
patent: 2001/0040130 (2001-11-01), Lorch et al.
patent: 2002/0055111 (2002-05-01), Chen et al.

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