Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-05-15
2007-05-15
Kim, Young J. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
Reexamination Certificate
active
10193742
ABSTRACT:
A method for preparing a nucleic acid component of a sample for amplification includes contacting the sample with a porous support that deactivates a nucleic acid amplification inhibitor component of the sample and directing a fluid through the porous support, whereby the nucleic acid component of the sample is directed through at least a portion of the porous support and is separated from the support, thereby preparing the nucleic acid component for amplification. The method can be conducted in an apparatus that includes a porous support having a component that deactivates a nucleic acid amplification inhibitor component of a sample contacting the porous support and a housing having an opening and defining an interior, said interior being in fluid communication with the porous support, whereby at least a portion of a fluid directed through the opening is directed through at least a portion of the porous support and separates at least a portion of a nucleic acid component of a sample contacting the porous support from the support, thereby preparing the nucleic acid component for amplification.
REFERENCES:
patent: 5234809 (1993-08-01), Boom et al.
patent: 5496562 (1996-03-01), Burgoyne
patent: 5660984 (1997-08-01), Davis et al.
patent: 5707850 (1998-01-01), Cole
patent: 5756126 (1998-05-01), Burgoyne
patent: 5804684 (1998-09-01), Su
patent: 5807527 (1998-09-01), Burgoyne
patent: 5840169 (1998-11-01), Andersen
patent: 5863801 (1999-01-01), Southgate et al.
patent: 5910246 (1999-06-01), Walter et al.
patent: 5939259 (1999-08-01), Harvey et al.
patent: 5972386 (1999-10-01), Burgoyne
patent: 5976572 (1999-11-01), Burgoyne
patent: 5985327 (1999-11-01), Burgoyne
patent: 6037465 (2000-03-01), Hillebrand et al.
patent: 6168922 (2001-01-01), Harvey et al.
patent: 6218176 (2001-04-01), Berthold et al.
patent: 6264814 (2001-07-01), Lange
patent: 6374684 (2002-04-01), Dority
patent: 6428962 (2002-08-01), Naegele
patent: 6431476 (2002-08-01), Taylor et al.
patent: 6440725 (2002-08-01), Pourahmadi et al.
patent: 6673631 (2004-01-01), Tereba et al.
patent: 2002/0042125 (2002-04-01), Peterson et al.
patent: WO 9913976 (1999-03-01), None
Brush, “PCR on the Run,” The Scientist, Jun. 26, 2000, vol. 14, No. 13, pp. 1-5.
S.N.A.P. MidiPrep Kit, Invitrogen Instruction Manual, Catalog No. K1910-01.
Smail et al., “Rapid, Cost-effective Gene Mutation Screening for Carnitine Palmitoyltransferase II Deficiency Using Whole Blood on Filter Paper,” Clinical Chemistry, 1999, vol. 45, No. 11, pp. 2035-2038.
Fiscus et al., “Quantitation of Human Immunodeficiency Virus Type 1 RNA in Plasma by Using Blood Dried on Filter Paper,” Journal of Clinical Microbiology, Jan. 1998, vol. 36, No. 1, pp. 258-260.
Chandler et al., “Automated nucleic acid isolation and purification from soil extracts using renewable affinity microcolumns in a sequential injection system,” Talanta 1999, vol. 49, pp. 969-983.
Itoh et al., “Automated Filtration-Based High-Throughput Plasmid Preparation System,” Genome Research, 1999, No. 9, pp. 463-470.
Andreotti, P., “Portable Swab Sample Processor (SSP) and Analyzer for Rapid Detection of Biothreat Agents,”Defense Advanced Research Projects Agency, Tissue Based Biosensors, Advanced Diagnostics, Activity Detection Technologies Principle Investigator Conference 2002, DARPA, Miami, Florida, Feb. 18-21, 2002.
Cepheid News; “Cepheid Collaborates on Major U.S. Postal Contract for Bio-threat Detection—Pilot Program to Employ GeneXpert® DNA-Detection System,” at http://www.cepheid.com/pages/press/020513.html, Sunnyvale, CA, May 13, 2002.
Levy, S., “A Fully Automated High-Throughput Nucleic Acid Purification System Using Silica Coated Magnetic Bead Technology,”Laboratory Robotics Interest Group, New England Chapter, Poster Session, Mar. 26, 2002, from http://www.lab-robotics.org/New—England/Posters/LRIG—New%20England%20Posters%20March%2026,2002.pdf.
Parameswaran, L., “Development of Recovery Techniques for Organisms and Nucleic Acids from Complex Samples”,Third Annual Biodetection Technologies 2003 International Symposium, from http://www.knowledgepress.com/event/12111105.htm.
Schmidt, J.C., “A Portable Biodetection System Incorporating Semi-Automated Sample Preparation,”Detection Technologies—The Next Generation in Identification and Analysis, Arlington, Virginia, Dec. 5-6, 2002, http://www.knowledgepress.com/events/7191716.htm.
Taylor, Michael T., et al., “Lysing Baterial Spores by Sonication through a Flexible Interface in a Microfluidic System,”Anal. Chem., 73:492-496 (2001).
Tu, Shu-I, et al., “Applications of Time-Resolved Fluoroimmunoassay to Detect Magnetic Bead CapturedEscherichia Coli0157:H7,”Journal of Rapid Methods and Automation in Microbiology, 9:71-84 (2001).
Cepheid Technology; “Fluidic Systems” at http://www.cepheid.com, Jun. 5, 2002.
“How GeneXpert Automates Sample Preparation,” at http://media.corporate-ir.net, Jun. 5, 2002.
“Cepheid Granted U.S. Patent Covering GeneXpert (R) Cartridge,” at http://biz.yahoo.com, Jun. 5, 2002.
Xtrana: Products: Nucleic Acid Testing; “SCIP: Self Contained Integrated Particle,” http://www.xtrana.com, Jun. 5, 2002.
Bobrow Johanna
Bortolin Laura T.
Harper James
Hollis Mark A.
Parameswaran Lalitha
Hamilton Brook Smith & Reynolds P.C.
Kim Young J.
Massachusetts Institute of Technology
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