Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1990-01-16
1992-01-07
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 50, 536 24, A61K 3170, C07H 1700
Patent
active
050792350
ABSTRACT:
The present invention relates to certain novel 5-substituted pyrimidine nucleosides and pharmaceutically acceptable derivatives thereof and their use in the treatment of varicella zoster virus, cytomegalovirus and Epstein Barr virus infections. Also provided are pharmaceutical formulations and processes for the preparation of the compounds according to the invention.
REFERENCES:
patent: 4267171 (1981-05-01), Bergstrom et al.
patent: 4274544 (1981-01-01), Bergstrom et al.
patent: 4863906 (1989-09-01), Rahim et al.
Goodchild et al., J. Med. Chem., 26, 1252-1257 (1983).
DeClercq, "Approaches to Antiviral Agents", Editor, Harnden, 1985.
DeClercq et al., J. Med. Chem., 26(5), pp. 661-666 (1983), Nucleic Acid Related Compounds, 40, Synthesis and Biological Activities of C-Alkynyluracil Nucleosides.
Giziewicz et al., Canadian J. Chem., pp. 147-151, vol. 62 (1984), The Crystal and Molecular Structure of 5-(propyn-1-yl)-1-(.beta.-D-arabinofuranosyl)uracil.
Balzarini et al., Methods and Find Exptl. Clin. Pharmacol, 7(1), 1985, pp. 19-28, Incorporation of 5-Substituted Pyrimidine Nucleoside Analogues into DNA of a Thymidylate Synthetase-Deficient Murine FM3A Carcinoma Cell Line.
Chem. Abs., vol. 91, 1979, pp. 26-27.
J. Med. Chem., 1984, 27(3), pp. 410-412.
Febs. Symp., 1979, 57, pp. 275-285.
Biochem. Pharmacol., 1983, 32(4), pp. 726-729.
Nucleic Acids Symp. Ser., 1981, 9, pp. 103-106.
Antimicrobial Agents Chemother., 1980, 17(6), pp. 1030-1031.
Antiviral Research, 1981, 1(4), pp. 213-223.
Nucleosides and Nucleotides, 1986, 5(5), pp. 571-578.
Antiviral Research, 4(3), pp. 159-168, 1984.
Int. Congr. Ser. Excerpta. Med. Herpes Virus Clin. Pharmacol. Basic Aspects, pp. 211-214, 1982.
Acta. Microbiol. Acad. Sci. Hung., 1981, 28(3), pp. 307-312.
Antiviral Chemother. Des. Inhib. Viral Function, 1981, Proc. Symp. Antiviral Chemotherap., pp. 207-217.
Antimicrob. Agents, 23(3), pp. 416-421, 1983.
Mol. Pharmacol. (1982), 21, pp. 217-223.
Nucleic. Acids Res. Spec. Pub. (1978), 4, pp. 103-106.
Purifoy Dorothy J. M.
Rahim Saad G.
Brown Donald
Burroughs Wellcome Co.
Rollins John W.
LandOfFree
Antiviral compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antiviral compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antiviral compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-822670