Antiviral compounds

Details Antiviral compounds Antiviral compounds

1995-05-16

1997-02-25

Guzo, David

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

Inactivation or attenuation; producing viral subunits

514183, C12N 704, A01N 4372, A01N 4390

Patent

active

056058284

ABSTRACT:
The macrolide FK506, produced by Fujisawa Pharmaceuticals is effective in inhibiting the replication of hepatitis D virus. It is believed that replication is inhibited either by virtue of the ability of FK506 to inhibit proline isomerase or otherwise to interfere with the function of a C-terminal proline in a replication factor or by virtue of its interference with RNA replication directly.

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