Antitumor compound, compositions and method of use

Organic compounds -- part of the class 532-570 series – Organic compounds – Halogen containing

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514744, 570238, C07C 2102, C07C 2114, A01N 2902, A61K 31035

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active

052833836

ABSTRACT:
The present invention relates to a new antitumor compound, a method for isolating same from a red alga, antitumor compositions containing same and methods of using same for treating patients with cancer. The compound of the present invention is 6(R)-bromo-3(S)-bromomethyl-7-methyl-2,3,7-trichloro-1-octene.

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Boyd, Michael R., Principles and Practice of Oncology Updates, ed. DeVita, Hellman & Rosenberg, vol. 3, #10, 1-12, 1989.
Burreson et al., Chemistry Letters 1111-1114, 1975.
Collins, Jerry M., Cancer Chemotherapy: Principles and Practice by Chabner and Collins, Chapter 2, J. B. Lippincott, Philadelphia, 1990.
Boyd et al., "Data Display and Analysis Strategies for the NCI Disease-Oriented In Vitro Antitumor Drug Screen", in Anticancer Drug Discovery and Development, eds Valerlote, F. A., Corbett, T. Baker, L.; Kluwer Academic Publishers, Amsterdam (in press 1990).
Monks et al., J. National Cancer Institute 83, No. 11, 757-766, 1991.
Boyd, Michael R. "The Future of Drug Development", in Current Therapy in Oncology; Section I. Introduction to Cancer Therapy; Chapter 2; ed Niederhuber; B. C. Decker, Inc., Philadelphia, (in press 1991).

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