Antimicrobial oil-in-water emulsions

Details Antimicrobial oil-in-water emulsions Antimicrobial oil-in-water emulsions

1994-10-13

1996-08-27

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

A61K 740

Patent

active

055499015

ABSTRACT:
An antimicrobial lipid-containing oil-in-water emulsion comprising an agent selected from the group consisting of glycerol monooleate, glycerol trioleate, glycerol monolaurate, and glycerol dilaurate as the primary lipid and a cationic halogen-containing compound having a C.sub.12 -C.sub.16 chain as a positive charge producing agent is disclosed. The antimicrobial emulsion can be used in the form of a pharmaceutical preparation to inhibit the growth of a wide variety of infectious pathogens.

REFERENCES:
patent: 4902720 (1990-02-01), Baldone
patent: 5039688 (1991-08-01), Lewis
McCutcheon's Detergents & Emulsifers 1971 Annual, (New Jersey: Allured Publishing Company 1971), pp. 49,86.
Remington's Pharmaceutical Sciences (1985), 17th Edition: pp. 317-318, 328.
Isaacson, P. G., "Gastric Lymphoma and Helicobacter Pylori" New England Journal of Medicine, vol. 330, No. 18, pp. 1310-1311, 5 May 1994.
Parsonnet, J. et al., "Helicobacter Pylori Infection and Gastric Lymphoma" New England Journal of Medicine, vol. 330, No. 18, pp. 1267-1271, 5 May 1994.

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