Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-03-23
1997-10-14
Jordan, Kimberly
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514648, 514895, A61K 31335, A61K 31135
Patent
active
056773315
ABSTRACT:
The invention relates to a synergistic antimalarial composition which comprises the antimalarial agent benflumetol and also an antimalarial agent from the artemisinine group such as artemether. The composition can be formulated into solid dosage forms such as tablets and is useful for the treatment of drug resistant malaria.
REFERENCES:
Deng, Chemical Abstracts, vol. 112, No. 7, Feb. 12, 1990 p. 1, Abstract No. 48094s.
Deng, Chinese Journal of Pharmaceuticals 1989, vol. 20, No. 8 pp. 372-376.
Who, "Practical Chemotherapy of Malaria", World Health Organization Technical Report Series 805 (1990).
Deng et al., Chemical Abstracts, vol. 114 p. 595 (1991), Abstract No. 6046p.
Wang et al., Chemical Abstracts, vol. 101, p. 385 (1984), Abstract No. 136941u.
CA 97(4): 28538h, Wang et al., 1982.
CA 113(5): 34389a, Sethi et al., 1988.
Merck Index, Therapeutic Catagory p. 16, 1989.
CA 103:134524, Lin et al., 1985.
Ding Deben
Li Guofu
Liu Guangyu
Ning Dianxi
Shan Chengqi
Ciba-Geigy AG
Institute of Microbiology and Epidemiology, Academy of Military
Jordan Kimberly
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